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Cialis use with foods and supplements

 An overview of the effects induced by different foods and supplements on Cialis action and effectiveness. Evaluation of the potential benefits and threats of the mentioned interactions

The effect of foods and supplements on Cialis efficiency

Every time a man is prescribed Cialis, he is warned about the hazards of its concomitant use with nitrates or Riociguat, for example. However, Tadalafil, which is the active substance in Cialis, can interact not only with the medications but also with a number of food products, drinks, and supplements. That’s why it is important to know as much about it as possible. Let’s learn the details together!

Cialis user and coffee lover. Can it be one person?

The statistic says that 50% of Americans are coffee drinkers. Both men and women drink coffee equally often. Hence, half of the people represented by this statistic are men. The other statistic claims that 18% of men aged around 20 years old suffer from erectile dysfunction. This figure grows significantly as they get older. By the age of 70, about 70% of men will suffer some erection difficulties.

Judging by these figures, it’s not difficult to understand that the bulk of men with ED drink coffee. But is it safe for them? Actually, it is, and for some men, coffee can even be beneficial when on Cialis.

The reason is that this drink stimulates the activity of the central nervous system and raises blood pressure. It means that men with hypotension can experience fewer side effects triggered by the blood-pressure-lowering effect of Cialis. Consequently, this category of patients can get more benefits when using Cialis with coffee.

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Citrulline. A supplement that can help ED and PAH

Tadalafil is equally effective in the therapy of erectile dysfunction and pulmonary arterial hypertension. However, as they say, there’s no limit to perfection, and any effect can be improved. Citrulline is an alpha-amino acid derived from watermelon. Getting into the human organism, citrulline is converted into arginine and acts as a direct NO donor, thus adding to the muscle relaxation and blood vessels dilatory effects.

Several clinical studies proved an increase in Tadalafil efficiency if used in combination with citrulline. Japanese scientists experimented on the effects citrulline in combination with Tadalafil induces in rats with pulmonary hypertension. Out of five groups of rats receiving different kinds of treatment, only those treated with Tadalafil and citrulline showed 91.7% survival rate. The results of using other drugs were significantly worse.

Another study conducted with the participation of men with ED also revealed a positive effect of Tadalafil-citrulline combination. Patients who had a poor response to Tadalafil itself showed a positive dynamic when citrulline was added to their treatment plan. Hence, concomitant use of Cialis and citrulline supplement has a beneficial effect on the diseases treated.

Grapefruit with Cialis. Risks estimation

Your pharmacist or general practitioner may tell you that you shouldn’t take Cialis together with grapefruit or grapefruit juice. But why does the product that can provide us with a dose of useful vitamin C becomes dangerous with ED pills?

The secret hides inside your gastrointestinal tract. The amount of a special enzyme that is responsible for the breakup of Tadalafil CYP3A4 can be reduced by 47% when you drink or eat even a small portion of grapefruit products. As a result, the speed of Tadalafil excretion from the organism slows down, and the medication stays in the body for too long. Gradually, the concentration of Tadalafil in the blood increases to dangerous levels.

The possible consequences of such a raise are side effects that may evolve even in men who would normally have no adverse reactions to Cialis. Besides, if the next dose of the drug is taken before the time the previous one leaves the body, there is a high probability of overdose.

 



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